OMERACT 2020: A virtual (R)evolution
نویسندگان
چکیده
Idiopathic inflammatory myopathies (IIM) are a group of diseases characterized by muscle weakness, which limit activities daily living. Patient Reported Outcomes Measurement Information System (PROMIS) is set outcome measures developed using NIH funding, but has not yet been studied in adult IIM. Currently, the most commonly used PROs IIM Health Assessment Questionnaire (HAQ-DI) and SF-36 physical function-10 (PF10), both have several limitations. In this study, we investigated psychometric properties PROMIS function-20 (PF-20) compared to HAQ-DI PF10.Patients with completed PF-20 six myositis core [manual testing (MMT), physician (MD-GDA), patient (PT-GDA) extra-muscular global disease activity, creatine kinase], PF10 functional tests [six-minute walk, timed up-and-go sit-to-stand tests] at monthly visits over 6-months. Total improvement score (TIS) 2016 ACR/EULAR response criteria was obtained as change.Fifty patients [mean age, 51.6; 60% females] were enrolled; 6 PM, 24 DM, 9 NM 11 AS. showed strong test-retest reliability when repeated 1-month. had moderate-strong correlations MD-GDA, PT-GDA, MMT, HAQ-DI, PF10, indicating good convergent validity. Change strongly correlated TIS demonstrating responsiveness. exhibited similar validity responsiveness; found ceiling effect.PROMIS demonstrates favorable large cohort offers distinct advantages.
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ژورنال
عنوان ژورنال: Seminars in Arthritis and Rheumatism
سال: 2021
ISSN: ['1532-866X', '0049-0172']
DOI: https://doi.org/10.1016/j.semarthrit.2021.04.002